Kinetics of inhibition of two forms of acetylcholinesterase from Panagrellus redivivus by organophosphorus and carbamate compounds
نویسنده
چکیده
lnillbition experiments with paraoxon revealed two types of acetylcholinesterases in Panagrellus redivivus i.e. a fast (F-component) and a slow reacting component (S-component). The F-component was thermostable and inactivated by Triton-X100, while the S-component was thermolabile and insensitive for Triton-X-100. The bimolecular rate constant for inhibition by paraoxon was 25.5 x 103 M-1min' for the F-component and 9.2 x 103 M-'min' for the S-component. Comparable differences in sensitivity between the two components were observed with oxamyl and aldicarb.
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